The roles of COX-2 in protozoan infection

Protozoan diseases cause great harm in animal husbandry and require human-provided medical treatment. Protozoan infection can induce changes in cyclooxygenase-2 (COX-2) expression. The role played by COX-2 in the response to protozoan infection is complex. COX-2 induces and regulates inflammation by...

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Detalles Bibliográficos
Autores principales: Wang, Xinlei, Chen, Jie, Zheng, Jingtong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978824/
https://www.ncbi.nlm.nih.gov/pubmed/36875123
http://dx.doi.org/10.3389/fimmu.2023.955616
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author Wang, Xinlei
Chen, Jie
Zheng, Jingtong
author_facet Wang, Xinlei
Chen, Jie
Zheng, Jingtong
author_sort Wang, Xinlei
collection PubMed
description Protozoan diseases cause great harm in animal husbandry and require human-provided medical treatment. Protozoan infection can induce changes in cyclooxygenase-2 (COX-2) expression. The role played by COX-2 in the response to protozoan infection is complex. COX-2 induces and regulates inflammation by promoting the synthesis of different prostaglandins (PGs), which exhibit a variety of biological activities and participate in pathophysiological processes in the body in a variety of ways. This review explains the roles played by COX-2 in protozoan infection and analyzes the effects of COX-2-related drugs in protozoan diseases.
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spelling pubmed-99788242023-03-03 The roles of COX-2 in protozoan infection Wang, Xinlei Chen, Jie Zheng, Jingtong Front Immunol Immunology Protozoan diseases cause great harm in animal husbandry and require human-provided medical treatment. Protozoan infection can induce changes in cyclooxygenase-2 (COX-2) expression. The role played by COX-2 in the response to protozoan infection is complex. COX-2 induces and regulates inflammation by promoting the synthesis of different prostaglandins (PGs), which exhibit a variety of biological activities and participate in pathophysiological processes in the body in a variety of ways. This review explains the roles played by COX-2 in protozoan infection and analyzes the effects of COX-2-related drugs in protozoan diseases. Frontiers Media S.A. 2023-02-16 /pmc/articles/PMC9978824/ /pubmed/36875123 http://dx.doi.org/10.3389/fimmu.2023.955616 Text en Copyright © 2023 Wang, Chen and Zheng https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Wang, Xinlei
Chen, Jie
Zheng, Jingtong
The roles of COX-2 in protozoan infection
title The roles of COX-2 in protozoan infection
title_full The roles of COX-2 in protozoan infection
title_fullStr The roles of COX-2 in protozoan infection
title_full_unstemmed The roles of COX-2 in protozoan infection
title_short The roles of COX-2 in protozoan infection
title_sort roles of cox-2 in protozoan infection
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978824/
https://www.ncbi.nlm.nih.gov/pubmed/36875123
http://dx.doi.org/10.3389/fimmu.2023.955616
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