Chemistry-led investigations into the mode of action of NAMPT activators, resulting in the discovery of non-pyridyl class NAMPT activators

The cofactor nicotinamide adenine dinucleotide (NAD(+)) plays a key role in a wide range of physiological processes and maintaining or enhancing NAD(+) levels is an established approach to enhancing healthy aging. Recently, several classes of nicotinamide phosphoribosyl transferase (NAMPT) activator...

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Detalles Bibliográficos
Autores principales: Tang, Siyuan, Garzon Sanz, Miguel, Smith, Oliver, Krämer, Andreas, Egbase, Daniel, Caton, Paul W., Knapp, Stefan, Butterworth, Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978853/
https://www.ncbi.nlm.nih.gov/pubmed/36873168
http://dx.doi.org/10.1016/j.apsb.2022.07.016

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