Nanopolyphenol rejuvenates microglial surveillance of multiple misfolded proteins through metabolic reprogramming

Microglial surveillance plays an essential role in clearing misfolded proteins such as amyloid-beta, tau, and α-synuclein aggregates in neurodegenerative diseases. However, due to the complex structure and ambiguous pathogenic species of the misfolded proteins, a universal approach to remove the mis...

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Detalles Bibliográficos
Autores principales: Wang, Dayuan, Gu, Xiao, Ma, Xinyi, Chen, Jun, Zhang, Qizhi, Yu, Zhihua, Li, Juan, Hu, Meng, Tan, Xiaofang, Tang, Yuyun, Xu, Jianrong, Xu, Minjun, Song, Qingxiang, Song, Huahua, Jiang, Gan, Tang, Zaiming, Gao, Xiaoling, Chen, Hongzhuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978858/
https://www.ncbi.nlm.nih.gov/pubmed/36873190
http://dx.doi.org/10.1016/j.apsb.2022.07.014

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