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Immunoglobulin a (IgA) Vasculitis in the Elderly

IgA vasculitis is a small vessel vasculitis mediated by the deposition of IgA immune complexes. It mostly occurs in children and is rare in adults, with increased severity and mortality in the latter. Its aetiology remains largely unknown, and its prognosis depends primarily on the extent of renal i...

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Autores principales: Girao, Adriana, Fernandes, José A, Mira, Filipe S, Pina, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978861/
https://www.ncbi.nlm.nih.gov/pubmed/36874655
http://dx.doi.org/10.7759/cureus.34422
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author Girao, Adriana
Fernandes, José A
Mira, Filipe S
Pina, Rui
author_facet Girao, Adriana
Fernandes, José A
Mira, Filipe S
Pina, Rui
author_sort Girao, Adriana
collection PubMed
description IgA vasculitis is a small vessel vasculitis mediated by the deposition of IgA immune complexes. It mostly occurs in children and is rare in adults, with increased severity and mortality in the latter. Its aetiology remains largely unknown, and its prognosis depends primarily on the extent of renal involvement. We present the case of a 71-year-old woman with purpuric lesions in both lower and upper limbs associated with fever, abdominal pain, vomiting and blood in her stools for the past month. The patient was diagnosed with IgA vasculitis and the full systemic involvement (renal, dermatological, intestinal, and cerebral) of the disease was identified with excellent response to parenteral corticotherapy.
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spelling pubmed-99788612023-03-03 Immunoglobulin a (IgA) Vasculitis in the Elderly Girao, Adriana Fernandes, José A Mira, Filipe S Pina, Rui Cureus Internal Medicine IgA vasculitis is a small vessel vasculitis mediated by the deposition of IgA immune complexes. It mostly occurs in children and is rare in adults, with increased severity and mortality in the latter. Its aetiology remains largely unknown, and its prognosis depends primarily on the extent of renal involvement. We present the case of a 71-year-old woman with purpuric lesions in both lower and upper limbs associated with fever, abdominal pain, vomiting and blood in her stools for the past month. The patient was diagnosed with IgA vasculitis and the full systemic involvement (renal, dermatological, intestinal, and cerebral) of the disease was identified with excellent response to parenteral corticotherapy. Cureus 2023-01-31 /pmc/articles/PMC9978861/ /pubmed/36874655 http://dx.doi.org/10.7759/cureus.34422 Text en Copyright © 2023, Girao et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Girao, Adriana
Fernandes, José A
Mira, Filipe S
Pina, Rui
Immunoglobulin a (IgA) Vasculitis in the Elderly
title Immunoglobulin a (IgA) Vasculitis in the Elderly
title_full Immunoglobulin a (IgA) Vasculitis in the Elderly
title_fullStr Immunoglobulin a (IgA) Vasculitis in the Elderly
title_full_unstemmed Immunoglobulin a (IgA) Vasculitis in the Elderly
title_short Immunoglobulin a (IgA) Vasculitis in the Elderly
title_sort immunoglobulin a (iga) vasculitis in the elderly
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978861/
https://www.ncbi.nlm.nih.gov/pubmed/36874655
http://dx.doi.org/10.7759/cureus.34422
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