Nifuroxazide Activates the Parthanatos to Overcome TMPRSS2:ERG Fusion-Positive Prostate Cancer

Fusion of the E-26 transformation-specific (ETS)-related gene (ERG) with transmembrane serine protease 2 (TMPRSS2) is a crucial step in the occurrence and progression of approximately 50% of prostate cancers. Despite significant progress in drug discovery, ERG inhibitors have yet to be approved for...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Chengxun, Zhang, Jiale, Wu, Qiming, Kumar, Anuj, Pan, Guihong, Kelvin, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Small Molecule Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978883/
https://www.ncbi.nlm.nih.gov/pubmed/36622760
http://dx.doi.org/10.1158/1535-7163.MCT-22-0159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978883/
https://www.ncbi.nlm.nih.gov/pubmed/36622760
http://dx.doi.org/10.1158/1535-7163.MCT-22-0159

Ejemplares similares