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Nifuroxazide Activates the Parthanatos to Overcome TMPRSS2:ERG Fusion-Positive Prostate Cancer

Fusion of the E-26 transformation-specific (ETS)-related gene (ERG) with transmembrane serine protease 2 (TMPRSS2) is a crucial step in the occurrence and progression of approximately 50% of prostate cancers. Despite significant progress in drug discovery, ERG inhibitors have yet to be approved for...

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Detalles Bibliográficos
Autores principales:	Li, Chengxun, Zhang, Jiale, Wu, Qiming, Kumar, Anuj, Pan, Guihong, Kelvin, David J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2023
Materias:	Small Molecule Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978883/ https://www.ncbi.nlm.nih.gov/pubmed/36622760 http://dx.doi.org/10.1158/1535-7163.MCT-22-0159

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