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Electron Paramagnetic Resonance Implemented with Multiple Harmonic Detections Successfully Maps Extracellular pH In Vivo
[Image: see text] Extracellular acidification indicates a metabolic shift in cancer cells and is, along with tissue hypoxia, a hallmark of tumor malignancy. Thus, non-invasive mapping of extracellular pH (pHe) is essential for researchers to understand the tumor microenvironment and to monitor tumor...
Autores principales: | Nakaoka, Ririko, Kato, Kazuhiro, Yamamoto, Kumiko, Yasui, Hironobu, Matsumoto, Shingo, Kirilyuk, Igor A., Khramtsov, Valery V., Inanami, Osamu, Hirata, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979135/ https://www.ncbi.nlm.nih.gov/pubmed/36725678 http://dx.doi.org/10.1021/acs.analchem.2c03194 |
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