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Effect of commercially pure titanium implant coated with calcium carbonate and nanohydroxyapatite mixture on osseointegration

In this research, rabbit femurs were implanted with CP Ti screws coated with a combination of CaCO(3) and nanohydroxyapatite, and the effect on osseointegration was assessed using histological and histomorphometric examination at 2 and 6 weeks. CaCO(3) and nanohydroxyapatite were combined with the E...

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Detalles Bibliográficos
Autores principales: Abdullah, Zainab Saleh, Mahmood, Mustafa Shaker, Abdul-Ameer, Faiza Mohammed Ali, Fatalla, Abdalbseet Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Carol Davila University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979178/
https://www.ncbi.nlm.nih.gov/pubmed/36873118
http://dx.doi.org/10.25122/jml-2022-0049
Descripción
Sumario:In this research, rabbit femurs were implanted with CP Ti screws coated with a combination of CaCO(3) and nanohydroxyapatite, and the effect on osseointegration was assessed using histological and histomorphometric examination at 2 and 6 weeks. CaCO(3) and nanohydroxyapatite were combined with the EPD to coat the surfaces of the CP Ti screws. The femurs of five male rabbits were implanted with coated and uncoated implant screws. Healing time was divided into two groups (2 and 6 weeks). After 2 and 6 weeks of implantation, the histological examination revealed an increase in the growth of bone cells for coated screws, and the histomorphometric analysis revealed an increase in the percentage of new bone formation (after 6 weeks, 5.08% for coated implants and 3.66% for uncoated implants). In addition, the uncoated implant, the CP Ti implant coated with a combination of CaCO(3) and nanohydroxyapatite, stimulated early bone development after two weeks and mineralization and maturation after six weeks.