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Honokiol alleviated neurodegeneration by reducing oxidative stress and improving mitochondrial function in mutant SOD1 cellular and mouse models of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease affecting both upper and lower motor neurons (MNs) with large unmet medical needs. Multiple pathological mechanisms are considered to contribute to the progression of ALS, including neuronal oxidative stress and mitochond...

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Detalles Bibliográficos
Autores principales: Zhou, Yujun, Tang, Jingshu, Lan, Jiaqi, Zhang, Yong, Wang, Hongyue, Chen, Qiuyu, Kang, Yuying, Sun, Yang, Feng, Xinhong, Wu, Lei, Jin, Hongtao, Chen, Shizhong, Peng, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979194/
https://www.ncbi.nlm.nih.gov/pubmed/36873166
http://dx.doi.org/10.1016/j.apsb.2022.07.019