Cargando…

Twenty-eight day repeated exposure of human 3D bronchial epithelial model to heated tobacco aerosols indicates decreased toxicological responses compared to cigarette smoke

Tobacco harm reduction (THR) involves providing adult smokers with potentially reduced harm modes of nicotine delivery as alternatives to smoking combustible cigarettes. Heated tobacco products (HTPs) form a category with THR potential due to their ability to deliver nicotine and flavours through he...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chapman, Fiona, Pour, Sarah Jean, Wieczorek, Roman, Trelles Sticken, Edgar, Budde, Jessica, Röwer, Karin, Otte, Sandra, Mason, Elizabeth, Czekala, Lukasz, Nahde, Thomas, O’Connell, Grant, Simms, Liam, Stevenson, Matthew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Toxicology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979258/ https://www.ncbi.nlm.nih.gov/pubmed/36875887 http://dx.doi.org/10.3389/ftox.2023.1076752

Ejemplares similares

Use of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes to Predict the Cardiotoxicity Potential of Next Generation Nicotine Products
por: Simms, Liam, et al.
Publicado: (2022)

Multi-endpoint analysis of human 3D airway epithelium following repeated exposure to whole electronic vapor product aerosol or cigarette smoke
por: Czekala, Lukasz, et al.
Publicado: (2021)

The in vitro ToxTracker and Aneugen Clastogen Evaluation extension assay as a tool in the assessment of relative genotoxic potential of e-liquids and their aerosols
por: Czekala, Lukasz, et al.
Publicado: (2021)

Use of a rapid human primary cell-based disease screening model, to compare next generation products to combustible cigarettes
por: Simms, Liam, et al.
Publicado: (2021)

The use of human induced pluripotent stem cells to screen for developmental toxicity potential indicates reduced potential for non-combusted products, when compared to cigarettes
por: Simms, Liam, et al.
Publicado: (2020)

Equine feed contamination and toxicology
por: Bischoff, Karyn, et al.
Publicado: (2018)

Implementation of Zebrafish Ontologies for Toxicology Screening
por: Thessen, Anne E., et al.
Publicado: (2022)

Editorial: Women in regulatory toxicology: 2021
por: Ågerstrand, Marlene, et al.
Publicado: (2022)

Ecological Thresholds of Toxicological Concern: A Review
por: Barron, Mace G., et al.
Publicado: (2021)

Editorial: Methods and Protocols in Developmental and Reproductive Toxicology
por: Hougaard, Karin Sørig, et al.
Publicado: (2022)

The Inclusion of Sex and Gender Beyond the Binary in Toxicology
por: King, Dillon E.
Publicado: (2022)

Editorial: Women in developmental and reproductive toxicology: 2021
por: Adibi, Jennifer J., et al.
Publicado: (2022)

Toxicological Assessment of Flavor Ingredients in E-Vapor Products
por: Sciuscio, Davide, et al.
Publicado: (2022)

Threshold of Toxicological Concern—An Update for Non-Genotoxic Carcinogens
por: Batke, Monika, et al.
Publicado: (2021)

Next Generation Reproductive and Developmental Toxicology: Crosstalk Into the Future
por: Hougaard, Karin Sørig
Publicado: (2021)

The green man enigma: Unique presentation of toxicology in the emergency department
por: Trotzky, Daniel, et al.
Publicado: (2021)

Insect in vitro System for Toxicology Studies — Current and Future Perspectives
por: Cc, Sheeja, et al.
Publicado: (2021)

Editorial: Advances and Refinements in the Development and Application of Threshold of Toxicological Concern
por: Patlewicz, Grace, et al.
Publicado: (2022)

Toxicologic Exposures in California Emergency Departments in 2011 and Its Risk Factors
por: Lotfipour, Shahram, et al.
Publicado: (2021)

Editorial: Mechanisms of Developmental and Reproductive Toxicology of Ultrafine and Nano-Sized Particles
por: Umezawa, Masakazu, et al.
Publicado: (2022)

Application of the Threshold of Toxicological Concern (TTC) in Food Safety: Challenges and Opportunities
por: Serafimova, Rositsa, et al.
Publicado: (2021)

Toxicological Impact and in Vivo Tracing of Rhodamine Functionalised ZIF-8 Nanoparticles
por: Goyal, Prateek, et al.
Publicado: (2022)

Toxicological impact of microplastics and nanoplastics on humans: understanding the mechanistic aspect of the interaction
por: Alqahtani, Saeed, et al.
Publicado: (2023)

An overview of the toxicology and toxicokinetics of fusarenon-X, a type B trichothecene mycotoxin
por: AUPANUN, Sawinee, et al.
Publicado: (2016)

Telephonic Medical Toxicology Service in a Low-Resource Setting: Setup, Challenges, and Opportunities
por: Hitti, Eveline, et al.
Publicado: (2021)

Particle Safety Assessment in Additive Manufacturing: From Exposure Risks to Advanced Toxicology Testing
por: Alijagic, Andi, et al.
Publicado: (2022)

Endocrine Disruptors in a New Era of Predictive Toxicology and Dealing With the “More is Different” Challenge
por: Svingen, Terje
Publicado: (2022)

Navigating the Minefield of Computational Toxicology and Informatics: Looking Back and Charting a New Horizon
por: Patlewicz, Grace
Publicado: (2020)

Unveiling the noxious effect of polystyrene microplastics in aquatic ecosystems and their toxicological behavior on fishes and microalgae
por: Jalaudin Basha, Nurin Nabilah, et al.
Publicado: (2023)

A Low-Serum Culture System for Prolonged in Vitro Toxicology Experiments on a Macrophage System
por: Dalzon, Bastien, et al.
Publicado: (2021)

Derivation of New Threshold of Toxicological Concern Values for Exposure via Inhalation for Environmentally-Relevant Chemicals
por: Nelms, Mark D., et al.
Publicado: (2020)

Methylmercury-induced cytotoxicity and oxidative biochemistry impairment in dental pulp stem cells: the first toxicological findings
por: de Souza-Rodrigues, Renata Duarte, et al.
Publicado: (2021)

Internal Threshold of Toxicological Concern (iTTC): Where We Are Today and What Is Possible in the Near Future
por: Ellison, Corie A., et al.
Publicado: (2021)

Development of a New Threshold of Toxicological Concern Database of Non-cancer Toxicity Endpoints for Industrial Chemicals
por: Yamada, Takashi, et al.
Publicado: (2021)

Navigating the bridge between wet and dry lab toxicology research to address current challenges with high-dimensional data
por: Payton, Alexis, et al.
Publicado: (2023)

Development of Microfluidic, Serum-Free Bronchial Epithelial Cells-on-a-Chip to Facilitate a More Realistic In vitro Testing of Nanoplastics
por: Gupta, Govind, et al.
Publicado: (2021)

A Census of Medicolegal Death Investigation in the United States: A Need to Determine the State of our Nation’s Toxicology Laboratories and Their Preparedness for the Current Drug Overdose Epidemic,
por: Ropero‐Miller, Jeri D., et al.
Publicado: (2020)

Discriminating Spontaneous From Cigarette Smoke and THS 2.2 Aerosol Exposure-Related Proliferative Lung Lesions in A/J Mice by Using Gene Expression and Mutation Spectrum Data
por: Xiang, Yang, et al.
Publicado: (2021)

Sex blind: bridging the gap between drug exposure and sex-related gene expression in Danio rerio using next-generation sequencing (NGS) data and a literature review to find the missing links in pharmaceutical and environmental toxicology studies
por: King, Alex C., et al.
Publicado: (2023)

Atrazine and Breast Cancer: A Framework Assessment of the Toxicological and Epidemiological Evidence
por: Simpkins, James W., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_5mnveov4n2qps98qhddcd185oi