A novel and low-toxic peptide DR3penA alleviates pulmonary fibrosis by regulating the MAPK/miR-23b-5p/AQP5 signaling axis

Pulmonary fibrosis (PF) is a pathological change caused by repeated injuries and repair dysfunction of the alveolar epithelium. Our previous study revealed that the residues Asn3 and Asn4 of peptide DR8 (DHNNPQIR-NH(2)) could be modified to improve stability and antifibrotic activity, and the unnatu...

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Detalles Bibliográficos
Autores principales: Wang, Dan, Deng, Bochuan, Cheng, Lu, Li, Jieru, Zhang, Jiao, Zhang, Xiang, Guo, Xiaomin, Yan, Tiantian, Yue, Xin, An, Yingying, Zhang, Bangzhi, Yang, Wenle, Xie, Junqiu, Wang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979266/
https://www.ncbi.nlm.nih.gov/pubmed/36873181
http://dx.doi.org/10.1016/j.apsb.2022.09.001

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