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New frontiers in immune checkpoint B7-H3 (CD276) research and drug development

B7-H3 (CD276), a member of the B7 family of proteins, is a key player in cancer progression. This immune checkpoint molecule is selectively expressed in both tumor cells and immune cells within the tumor microenvironment. In addition to its immune checkpoint function, B7-H3 has been linked to tumor...

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Detalles Bibliográficos
Autores principales: Getu, Ayechew Adera, Tigabu, Abiye, Zhou, Ming, Lu, Jianrong, Fodstad, Øystein, Tan, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979440/
https://www.ncbi.nlm.nih.gov/pubmed/36859240
http://dx.doi.org/10.1186/s12943-023-01751-9