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The promotive role of USP1 inhibition in coordinating osteogenic differentiation and fracture healing during nonunion

BACKGROUND: Nonunion is a failure of fracture healing and a major complication after fractures. Ubiquitin-specific protease 1 (USP1) is a deubiquitinase that involved in cell differentiation and cell response to DNA damage. Herein we investigated the expression, function and mechanism of USP1 in non...

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Detalles Bibliográficos
Autores principales: Huang, Jun, Zhou, Hongxiang, He, Liang, Zhong, Lin, Zhou, Ding, Yin, Zongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979441/
https://www.ncbi.nlm.nih.gov/pubmed/36859264
http://dx.doi.org/10.1186/s13018-023-03594-y