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The promotive role of USP1 inhibition in coordinating osteogenic differentiation and fracture healing during nonunion
BACKGROUND: Nonunion is a failure of fracture healing and a major complication after fractures. Ubiquitin-specific protease 1 (USP1) is a deubiquitinase that involved in cell differentiation and cell response to DNA damage. Herein we investigated the expression, function and mechanism of USP1 in non...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979441/ https://www.ncbi.nlm.nih.gov/pubmed/36859264 http://dx.doi.org/10.1186/s13018-023-03594-y |