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Metabolic engineering for the biosynthesis of bis-indolylquinone terrequinone A in Escherichia coli from L-tryptophan and prenol

BACKGROUND: Terrequinone A is a bis-indolylquinone natural product with antitumor activity. Due to its unique asymmetric quinone core structure and multiple functional groups, biosynthesis is more efficient and environmentally friendly than traditional chemical synthesis. Currently, most bis-indolyl...

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Detalles Bibliográficos
Autores principales:	Wang, Lijuan, Deng, Yongdong, Peng, Rihe, Gao, Jianjie, Li, Zhenjun, Zhang, Wenhui, Xu, Jing, Wang, Bo, Wang, Yu, Han, Hongjuan, Fu, Xiaoyan, Tian, Yongsheng, Yao, Quanhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979454/ https://www.ncbi.nlm.nih.gov/pubmed/36859334 http://dx.doi.org/10.1186/s13068-023-02284-5

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