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BMP7 ameliorates intervertebral disc degeneration in type 1 diabetic rats by inhibiting pyroptosis of nucleus pulposus cells and NLRP3 inflammasome activity

BACKGROUND: Accumulating evidence indicates that intervertebral disc degeneration (IDD) is associated with diabetes mellitus (DM), while the underlying mechanisms still remain elusive. Herein, the current study sought to explore the potential molecular mechanism of IDD in diabetic rats based on tran...

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Detalles Bibliográficos
Autores principales: Yu, Xiao-Jun, Wang, Ying-Guang, Lu, Rui, Guo, Xin-Zhen, Qu, Yun-Kun, Wang, Shan-Xi, Xu, Hao-Ran, Kang, Hao, You, Hong-Bo, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979491/
https://www.ncbi.nlm.nih.gov/pubmed/36858954
http://dx.doi.org/10.1186/s10020-023-00623-8