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BMP7 ameliorates intervertebral disc degeneration in type 1 diabetic rats by inhibiting pyroptosis of nucleus pulposus cells and NLRP3 inflammasome activity
BACKGROUND: Accumulating evidence indicates that intervertebral disc degeneration (IDD) is associated with diabetes mellitus (DM), while the underlying mechanisms still remain elusive. Herein, the current study sought to explore the potential molecular mechanism of IDD in diabetic rats based on tran...
Autores principales: | Yu, Xiao-Jun, Wang, Ying-Guang, Lu, Rui, Guo, Xin-Zhen, Qu, Yun-Kun, Wang, Shan-Xi, Xu, Hao-Ran, Kang, Hao, You, Hong-Bo, Xu, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979491/ https://www.ncbi.nlm.nih.gov/pubmed/36858954 http://dx.doi.org/10.1186/s10020-023-00623-8 |
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