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Amino acid substitutions in specific proteins correlate with farnesol unresponsiveness in Candida albicans

BACKGROUND: The quorum-sensing molecule farnesol, in opportunistic yeast Candida albicans, modulates its dimorphic switch between yeast and hyphal forms, and biofilm formation. Although there is an increasing interest in farnesol as a potential antifungal drug, the molecular mechanism by which C. al...

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Detalles Bibliográficos
Autores principales: Mohammadi, Sima, Leduc, Annie, Charette, Steve J., Barbeau, Jean, Vincent, Antony T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979538/
https://www.ncbi.nlm.nih.gov/pubmed/36859182
http://dx.doi.org/10.1186/s12864-023-09174-y