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Health effects of the time-restricted eating in adults with obesity: A systematic review and meta-analysis
BACKGROUND: The number of people suffering from overweight or obesity has been steadily increasing in recent years. As a new form of diet, the efficacy of time-restricted eating (TRE) remains debatable. OBJECTIVE: This meta-analysis quantified the effect of TRE on weight change and other physical pa...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979543/ https://www.ncbi.nlm.nih.gov/pubmed/36875837 http://dx.doi.org/10.3389/fnut.2023.1079250 |
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author | Chen, Weiyi Liu, Xiaoli Bao, Lei Yang, Ping Zhou, Huihui |
author_facet | Chen, Weiyi Liu, Xiaoli Bao, Lei Yang, Ping Zhou, Huihui |
author_sort | Chen, Weiyi |
collection | PubMed |
description | BACKGROUND: The number of people suffering from overweight or obesity has been steadily increasing in recent years. As a new form of diet, the efficacy of time-restricted eating (TRE) remains debatable. OBJECTIVE: This meta-analysis quantified the effect of TRE on weight change and other physical parameters in obese and overweight adults. METHODS: We did a systematic review and meta-analysis of randomized controlled trials (RCTs) comparing the TRE interventions on weight loss and other metabolic parameters by searching PubMed, Embase, and Cochrane Central Register of Controlled Trials to identify eligible trials published from database inception up until 23 August 2022. The risk of bias was assessed using the Revised Cochrane risk-of-bias tool (ROB-2.0). Meta-analysis was performed using Review Manager 5.4.1 software. RESULTS: Nine RCTs with 665 individuals (345 in the TRE group while 320 in the control group) were included. Results indicated that TRE had a greater decrease in body weight (−1.28 kg; 95% CI [−2.05, −0.52], p = 0.001), fat mass (−0.72 kg; 95% CI [−1.40, −0.03], p = 0.04), body mass index (−0.34 kg/m(2); 95% CI [−0.64, −0.04], p = 0.03) and diastolic blood pressure (−2.26 mmHg 95% CI [−4.02, −0.50], p = 0.01). However, the meta-analysis demonstrated that there was no significant difference between TRE and the control group in lean mass, systolic blood pressure, waist circumference, fasting glucose, fasting insulin, homeostasis model assessment-insulin resistance (HOMA-IR), total cholesterol, high-density lipoprotein, low-density lipoprotein, and triglycerides. Besides, the duration of the study and daily eating window also had an impact on weight change. CONCLUSION: TRE was associated with reductions in weight and fat mass and can be a dietary intervention option for adults with obesity. But high-quality trials and longer follow-ups are needed to draw definitive conclusions. |
format | Online Article Text |
id | pubmed-9979543 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-99795432023-03-03 Health effects of the time-restricted eating in adults with obesity: A systematic review and meta-analysis Chen, Weiyi Liu, Xiaoli Bao, Lei Yang, Ping Zhou, Huihui Front Nutr Nutrition BACKGROUND: The number of people suffering from overweight or obesity has been steadily increasing in recent years. As a new form of diet, the efficacy of time-restricted eating (TRE) remains debatable. OBJECTIVE: This meta-analysis quantified the effect of TRE on weight change and other physical parameters in obese and overweight adults. METHODS: We did a systematic review and meta-analysis of randomized controlled trials (RCTs) comparing the TRE interventions on weight loss and other metabolic parameters by searching PubMed, Embase, and Cochrane Central Register of Controlled Trials to identify eligible trials published from database inception up until 23 August 2022. The risk of bias was assessed using the Revised Cochrane risk-of-bias tool (ROB-2.0). Meta-analysis was performed using Review Manager 5.4.1 software. RESULTS: Nine RCTs with 665 individuals (345 in the TRE group while 320 in the control group) were included. Results indicated that TRE had a greater decrease in body weight (−1.28 kg; 95% CI [−2.05, −0.52], p = 0.001), fat mass (−0.72 kg; 95% CI [−1.40, −0.03], p = 0.04), body mass index (−0.34 kg/m(2); 95% CI [−0.64, −0.04], p = 0.03) and diastolic blood pressure (−2.26 mmHg 95% CI [−4.02, −0.50], p = 0.01). However, the meta-analysis demonstrated that there was no significant difference between TRE and the control group in lean mass, systolic blood pressure, waist circumference, fasting glucose, fasting insulin, homeostasis model assessment-insulin resistance (HOMA-IR), total cholesterol, high-density lipoprotein, low-density lipoprotein, and triglycerides. Besides, the duration of the study and daily eating window also had an impact on weight change. CONCLUSION: TRE was associated with reductions in weight and fat mass and can be a dietary intervention option for adults with obesity. But high-quality trials and longer follow-ups are needed to draw definitive conclusions. Frontiers Media S.A. 2023-02-16 /pmc/articles/PMC9979543/ /pubmed/36875837 http://dx.doi.org/10.3389/fnut.2023.1079250 Text en Copyright © 2023 Chen, Liu, Bao, Yang and Zhou. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Nutrition Chen, Weiyi Liu, Xiaoli Bao, Lei Yang, Ping Zhou, Huihui Health effects of the time-restricted eating in adults with obesity: A systematic review and meta-analysis |
title | Health effects of the time-restricted eating in adults with obesity: A systematic review and meta-analysis |
title_full | Health effects of the time-restricted eating in adults with obesity: A systematic review and meta-analysis |
title_fullStr | Health effects of the time-restricted eating in adults with obesity: A systematic review and meta-analysis |
title_full_unstemmed | Health effects of the time-restricted eating in adults with obesity: A systematic review and meta-analysis |
title_short | Health effects of the time-restricted eating in adults with obesity: A systematic review and meta-analysis |
title_sort | health effects of the time-restricted eating in adults with obesity: a systematic review and meta-analysis |
topic | Nutrition |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979543/ https://www.ncbi.nlm.nih.gov/pubmed/36875837 http://dx.doi.org/10.3389/fnut.2023.1079250 |
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