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Exogenous monocyte myeloid-derived suppressor cells ameliorate immune imbalance, neuroinflammation and cognitive impairment in 5xFAD mice infected with Porphyromonas gingivalis

BACKGROUND: Periodontitis is closely associated with the pathogenesis of Alzheimer’s disease (AD). Porphyromonas gingivalis (Pg), the keystone periodontal pathogen, has been reported in our recent study to cause immune-overreaction and induce cognitive impairment. Monocytic myeloid-derived suppresso...

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Detalles Bibliográficos
Autores principales:	Cheng, Xiao, Chi, Li, Lin, Tianqiong, Liang, Fengyin, Pei, Zhong, Sun, Jianbo, Teng, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979576/ https://www.ncbi.nlm.nih.gov/pubmed/36864466 http://dx.doi.org/10.1186/s12974-023-02743-8

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