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Pharmacokinetics and pharmacodynamics of imatinib for optimal drug repurposing from cancer to COVID-19

INTRODUCTION: In the randomized double-blind placebo-controlled CounterCOVID study, oral imatinib treatment conferred a positive clinical outcome and a signal for reduced mortality in COVID-19 patients. High concentrations of alpha-1 acid glycoprotein (AAG) were observed in these patients and were a...

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Detalles Bibliográficos
Autores principales:	Baalbaki, Nadia, Duijvelaar, Erik, Said, Medhat M., Schippers, Job, Bet, Pierre M., Twisk, Jos, Fritchley, Sarah, Longo, Cristina, Mahmoud, Kazien, Maitland-van der Zee, Anke H., Bogaard, Harm Jan, Swart, Eleonora L., Aman, Jurjan, Bartelink, Imke H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Authors. Published by Elsevier B.V. 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979628/ https://www.ncbi.nlm.nih.gov/pubmed/36870577 http://dx.doi.org/10.1016/j.ejps.2023.106418

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