Therapie von COVID-19 unter Berücksichtigung von Lebererkrankungen

Patients with chronic liver disease (CLD), especially cirrhosis, and immunosuppressed post-liver transplant patients generally appear to be at increased risk of infection, resulting in increased mortality. This is also evident in severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection, where patients with cirrhosis in particular are at high risk for coronavirus disease 2019 (COVID-19). Prevention and treatment of SARS-CoV‑2 infection are therefore important measures to protect this vulnerable group of patients from the consequences of COVID-19. The recent SARS-CoV‑2 pandemic has led to exceptionally rapid development of vaccines, prophylactic and therapeutic antibodies, as well as testing of new drugs and drugs already approved for other indications. In this article, we summarize therapeutic approaches with special consideration of patients with chronic liver disease and patients after liver transplantation.