Structures of chloramphenicol acetyltransferase III and Escherichia coli β-ketoacylsynthase III co-crystallized with partially hydrolysed acetyl-oxa(dethia)CoA

Acetyl coenzyme A (acetyl-CoA) is a reactive metabolite that nonproductively hydrolyzes in a number of enzyme active sites in the crystallization time frame. In order to elucidate the enzyme–acetyl-CoA interactions leading to catalysis, acetyl-CoA substrate analogs are needed. One possible analog fo...

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Detalles Bibliográficos
Autores principales: Benjamin, Aaron B., Stunkard, Lee M., Ling, Jianheng, Nice, Jaelen N., Lohman, Jeremy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2023
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979976/
https://www.ncbi.nlm.nih.gov/pubmed/36862094
http://dx.doi.org/10.1107/S2053230X23001206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9979976/
https://www.ncbi.nlm.nih.gov/pubmed/36862094
http://dx.doi.org/10.1107/S2053230X23001206

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