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Augmentation of Histone Deacetylase 6 Activity Impairs Mitochondrial Respiratory Complex I in Ischemic/Reperfused Diabetic Hearts

BACKGROUND: Diabetes augments activity of histone deacetylase 6 (HDAC6) and generation of tumor necrosis factor α (TNFα) and impairs the physiological function of mitochondrial complex I (mCI) which oxidizes reduced nicotinamide adenine dinucleotide (NADH) to nicotinamide adenine dinucleotide to sus...

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Detalles Bibliográficos
Autores principales:	Baumgardt, Shelley L., Fang, Juan, Fu, Xuebin, Liu, Yanan, Xia, Zhengyuan, Zhao, Ming, Chen, Ling, Mishra, Rachana, Gunasekaran, Muthukumar, Saha, Progyaparamita, Forbess, Joseph M., Bosnjak, Zeljko J., Camara, Amadou KS, Kersten, Judy R., Thorp, Edward, Kaushal, Sunjay, Ge, Zhi-Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980088/ https://www.ncbi.nlm.nih.gov/pubmed/36865233 http://dx.doi.org/10.1101/2023.02.21.529462

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