The ATM-E6AP-MASTL axis mediates DNA damage checkpoint recovery

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Checkpoint activation after DNA damage causes a transient cell cycle arrest by suppressing CDKs. However, it remains largely elusive how cell cycle recovery is initiated after DNA damage. In this study, we discovered the upregulated protein level of MASTL kinase hours after DNA damage. MASTL promote...

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Detalles Bibliográficos
Autores principales: Li, Yanqiu, Wang, Feifei, Li, Xin, Wang, Ling, Yang, Zheng, You, Zhongsheng, Peng, Aimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980089/
https://www.ncbi.nlm.nih.gov/pubmed/36865136
http://dx.doi.org/10.1101/2023.02.22.529521
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