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Phased nanopore assembly with Shasta and modular graph phasing with GFAse

As a step towards simplifying and reducing the cost of haplotype resolved de novo assembly, we describe new methods for accurately phasing nanopore data with the Shasta genome assembler and a modular tool for extending phasing to the chromosome scale called GFAse. We test using new variants of Oxfor...

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Detalles Bibliográficos
Autores principales: Lorig-Roach, Ryan, Meredith, Melissa, Monlong, Jean, Jain, Miten, Olsen, Hugh, McNulty, Brandy, Porubsky, David, Montague, Tessa, Lucas, Julian, Condon, Chris, Eizenga, Jordan, Juul, Sissel, McKenzie, Sean, Simmonds, Sara E., Park, Jimin, Asri, Mobin, Koren, Sergey, Eichler, Evan, Axel, Richard, Martin, Bruce, Carnevali, Paolo, Miga, Karen, Paten, Benedict
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980101/
https://www.ncbi.nlm.nih.gov/pubmed/36865218
http://dx.doi.org/10.1101/2023.02.21.529152