A cell state specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma

Glioma cells hijack developmental transcriptional programs to control cell state. During neural development, lineage trajectories rely on specialized metabolic pathways. However, the link between tumor cell state and metabolic programs is poorly understood in glioma. Here we uncover a glioma cell st...

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Detalles Bibliográficos
Autores principales: Banu, Matei A., Dovas, Athanassios, Argenziano, Michael G., Zhao, Wenting, Grajal, Henar Cuervo, Higgins, Dominique M.O., Sperring, Colin P., Pereira, Brianna, Ye, Ling F., Mahajan, Aayushi, Humala, Nelson, Furnari, Julia L., Upadhyayula, Pavan S., Zandkarimi, Fereshteh, Nguyen, Trang T. T., Wu, Peter B., Hai, Li, Karan, Charles, Razavilar, Aida, Siegelin, Markus D., Kitajewski, Jan, Bruce, Jeffrey N., Stockwell, Brent R., Sims, Peter A., Canoll, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980114/
https://www.ncbi.nlm.nih.gov/pubmed/36865302
http://dx.doi.org/10.1101/2023.02.22.529581

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