Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against Mycobacterium tuberculosis

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As one of the most successful human pathogens, Mycobacterium tuberculosis (Mtb) has evolved a diverse array of determinants to subvert host immunity and alter host metabolic patterns. However, the mechanisms of pathogen interference with host metabolism remain poorly understood. Here we show that a...

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Detalles Bibliográficos
Autores principales: Parveen, Sadiya, Shen, Jessica, Lun, Shichun, Zhao, Liang, Koleske, Benjamin, Leone, Robert D., Rais, Rana, Powell, Jonathan D., Murphy, John R., Slusher, Barbara S., Bishai, William R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980128/
https://www.ncbi.nlm.nih.gov/pubmed/36865287
http://dx.doi.org/10.1101/2023.02.23.529704

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