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Structural basis of histone H2A lysine 119 deubiquitination by Polycomb Repressive Deubiquitinase BAP1/ASXL1

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The maintenance of gene expression patterns during metazoan development is achieved by the actions of Polycomb group (PcG) complexes. An essential modification marking silenced genes is monoubiquitination of histone H2A lysine 119 (H2AK119Ub) deposited by the E3 ubiquitin ligase activity of the non-...

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Detalles Bibliográficos
Autores principales:	Thomas, Jonathan F., Valencia-Sánchez, Marco Igor, Tamburri, Simone, Gloor, Susan L., Rustichelli, Samantha, Godínez-López, Victoria, De Ioannes, Pablo, Lee, Rachel, Abini-Agbomson, Stephen, Gretarsson, Kristjan, Burg, Jonathan M., Hickman, Allison R., Sun, Lu, Gopinath, Saarang, Taylor, Hailey, Meiners, Matthew J., Cheek, Marcus A., Rice, William, Nudler, Evgeny, Lu, Chao, Keogh, Michael-Christopher, Pasini, Diego, Armache, Karim-Jean
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980132/ https://www.ncbi.nlm.nih.gov/pubmed/36865140 http://dx.doi.org/10.1101/2023.02.23.529554

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