Multiviral Quartet Nanocages Elicit Broad Anti-Coronavirus Responses for Proactive Vaccinology

Defending against future pandemics may require vaccine platforms that protect across a range of related pathogens. The presentation of multiple receptor-binding domains (RBDs) from evolutionarily-related viruses on a nanoparticle scaffold elicits a strong antibody response to conserved regions. Here...

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Detalles Bibliográficos
Autores principales: Hills, Rory A., Kit Tan, Tiong, Cohen, Alexander A., Keeffe, Jennifer R., Keeble, Anthony H., Gnanapragasam, Priyanthi N.P., Storm, Kaya N., Hill, Michelle L., Liu, Sai, Gilbert-Jaramillo, Javier, Afzal, Madeeha, Napier, Amy, James, William S., Bjorkman, Pamela J., Townsend, Alain R., Howarth, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980174/
https://www.ncbi.nlm.nih.gov/pubmed/36865256
http://dx.doi.org/10.1101/2023.02.24.529520

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