LRRC23 truncation impairs radial spoke 3 head assembly and sperm motility underlying male infertility

Radial spokes (RS) are T-shaped multiprotein complexes on the axonemal microtubules. Repeated RS1, RS2, and RS3 couple the central pair to modulate ciliary and flagellar motility. Despite the cell type specificity of RS3 substructures, their molecular components remain largely unknown. Here, we repo...

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Detalles Bibliográficos
Autores principales: Hwang, Jae Yeon, Chai, Pengxin, Nawaz, Shoaib, Choi, Jungmin, Lopez-Giraldez, Francesc, Hussain, Shabir, Bilguvar, Kaya, Mane, Shrikant, Lifton, Richard P., Ahmad, Wasim, Zhang, Kai, Chung, Jean-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980178/
https://www.ncbi.nlm.nih.gov/pubmed/36865175
http://dx.doi.org/10.1101/2023.02.25.530050

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