Optimized SMRT-UMI protocol produces highly accurate sequence datasets from diverse populations – application to HIV-1 quasispecies

Pathogen diversity resulting in quasispecies can enable persistence and adaptation to host defenses and therapies. However, accurate quasispecies characterization can be impeded by errors introduced during sample handling and sequencing which can require extensive optimizations to overcome. We prese...

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Detalles Bibliográficos
Autores principales: Westfall, Dylan H., Deng, Wenjie, Pankow, Alec, Murrell, Hugh, Chen, Lennie, Zhao, Hong, Williamson, Carolyn, Rolland, Morgane, Murrell, Ben, Mullins, James I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980183/
https://www.ncbi.nlm.nih.gov/pubmed/36865215
http://dx.doi.org/10.1101/2023.02.23.529831

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