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Synthesis and preclinical evaluation of a novel fluorine-18 labeled small-molecule PET radiotracer for Imaging of CXCR3 receptor In mouse models of atherosclerosis
BACKGROUND: CXCR3 is a chemokine receptor and is expressed on innate and adaptive immune cells. It promotes the recruitment of T-lymphocytes and other immune cells to the inflammatory site in response to the binding of cognate chemokines. Upregulation of CXCR3 and its chemokines has been found durin...
Autores principales: | Alluri, Santosh R., Higashi, Yusuke, Berendzen, Ashley, Grisanti, Laurel A., Watkinson, Lisa D., Singh, Kamlendra, Hoffman, Timothy J., Carmack, Terry, Devanny, Elizabeth A., Tanner, Miles, Kil, Kun-Eek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980197/ https://www.ncbi.nlm.nih.gov/pubmed/36865232 http://dx.doi.org/10.21203/rs.3.rs-2539952/v1 |
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