Synthesis and preclinical evaluation of a novel fluorine-18 labeled small-molecule PET radiotracer for Imaging of CXCR3 receptor In mouse models of atherosclerosis

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BACKGROUND: CXCR3 is a chemokine receptor and is expressed on innate and adaptive immune cells. It promotes the recruitment of T-lymphocytes and other immune cells to the inflammatory site in response to the binding of cognate chemokines. Upregulation of CXCR3 and its chemokines has been found durin...

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Detalles Bibliográficos
Autores principales: Alluri, Santosh R., Higashi, Yusuke, Berendzen, Ashley, Grisanti, Laurel A., Watkinson, Lisa D., Singh, Kamlendra, Hoffman, Timothy J., Carmack, Terry, Devanny, Elizabeth A., Tanner, Miles, Kil, Kun-Eek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980197/
https://www.ncbi.nlm.nih.gov/pubmed/36865232
http://dx.doi.org/10.21203/rs.3.rs-2539952/v1
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