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Higher testosterone and testosterone/estradiol ratio in men are associated with better epigenetic estimators of mortality risk

INTRODUCTION: Sex hormones are hypothesized to drive sex-specific health disparities. Here, we study the association between sex steroid hormones and DNA methylation-based (DNAm) biomarkers of age and mortality risk including Pheno Age Acceleration (AA), Grim AA, and DNAm-based estimators of Plasmin...

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Detalles Bibliográficos
Autores principales:	Kusters, Cynthia DJ, Paul, Kimberly C, Lu, Ake T, Ferrucci, Luigi, Ritz, Beate R, Binder, Alexandra M, Horvath, Steve
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980235/ https://www.ncbi.nlm.nih.gov/pubmed/36865294 http://dx.doi.org/10.1101/2023.02.16.23285997

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