The lamin A/C Ig-fold undergoes cell density-dependent changes that alter epitope binding

Lamins A/C are nuclear intermediate filament proteins that are involved in diverse cellular mechanical and biochemical functions. Here, we report that recognition of Lamins A/C by a commonly used antibody (JOL-2) that binds the Lamin A/C Ig-fold and other antibodies targeting similar epitopes is hig...

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Detalles Bibliográficos
Autores principales: Wallace, Melanie, Fedorchak, Gregory R., Agrawal, Richa, Gilbert, Rachel M., Patel, Jineet, Park, Sangwoo, Paszek, Matthew, Lammerding, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980629/
https://www.ncbi.nlm.nih.gov/pubmed/36809122
http://dx.doi.org/10.1080/19491034.2023.2180206

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