Multiple tissue-specific epigenetic alterations regulate persistent gene expression changes following developmental DES exposure in mouse reproductive tissues

Clinically, developmental exposure to the endocrine disrupting chemical, diethylstilboestrol (DES), results in long-term male and female infertility. Experimentally, developmental exposure to DES results in abnormal reproductive tract phenotypes in male and female mice. Previously, we reported that...

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Detalles Bibliográficos
Autores principales: Jefferson, Tanner B., Wang, Tianyuan, Jefferson, Wendy N., Li, Yin, Hamilton, Katherine J., Wade, Paul A., Williams, Carmen J., Korach, Kenneth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980695/
https://www.ncbi.nlm.nih.gov/pubmed/36328762
http://dx.doi.org/10.1080/15592294.2022.2139986

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