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Creation of an ustekinumab external control arm for Crohn’s disease using electronic health records data: A pilot study

BACKGROUND: Randomized trials are the gold-standard for clinical evidence generation, but they can sometimes be limited by infeasibility and unclear generalizability to real-world practice. External control arm (ECA) studies may help address this evidence gaps by constructing retrospective cohorts t...

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Detalles Bibliográficos
Autores principales: Rudrapatna, Vivek A., Cheng, Yao-Wen, Feuille, Colin, Mosenia, Arman, Shih, Jonathan, Shi, Yongmei, Roberson, Olivia, Rubin, Benjamin, Butte, Atul J., Mahadevan, Uma, Skomrock, Nicholas, Erondu, Ngozi, Chehoud, Christel, Rahim, Saquib, Apfel, David, Curran, Mark, Khan, Najat S., O’Brien, Christopher, Terry, Natalie, Martini, Benjamin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980824/
https://www.ncbi.nlm.nih.gov/pubmed/36862717
http://dx.doi.org/10.1371/journal.pone.0282267

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