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Creation of an ustekinumab external control arm for Crohn’s disease using electronic health records data: A pilot study
BACKGROUND: Randomized trials are the gold-standard for clinical evidence generation, but they can sometimes be limited by infeasibility and unclear generalizability to real-world practice. External control arm (ECA) studies may help address this evidence gaps by constructing retrospective cohorts t...
Autores principales: | Rudrapatna, Vivek A., Cheng, Yao-Wen, Feuille, Colin, Mosenia, Arman, Shih, Jonathan, Shi, Yongmei, Roberson, Olivia, Rubin, Benjamin, Butte, Atul J., Mahadevan, Uma, Skomrock, Nicholas, Erondu, Ngozi, Chehoud, Christel, Rahim, Saquib, Apfel, David, Curran, Mark, Khan, Najat S., O’Brien, Christopher, Terry, Natalie, Martini, Benjamin D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980824/ https://www.ncbi.nlm.nih.gov/pubmed/36862717 http://dx.doi.org/10.1371/journal.pone.0282267 |
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