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Uptake of severe acute respiratory syndrome coronavirus 2 spike protein mediated by angiotensin converting enzyme 2 and ganglioside in human cerebrovascular cells

INTRODUCTION: There is clinical evidence of neurological manifestations in coronavirus disease-19 (COVID-19). However, it is unclear whether differences in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/spike protein (SP) uptake by cells of the cerebrovasculature contribute to signific...

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Detalles Bibliográficos
Autores principales: McQuaid, Conor, Solorzano, Alexander, Dickerson, Ian, Deane, Rashid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980911/
https://www.ncbi.nlm.nih.gov/pubmed/36875642
http://dx.doi.org/10.3389/fnins.2023.1117845