MYCMI-7: A Small MYC-Binding Compound that Inhibits MYC: MAX Interaction and Tumor Growth in a MYC-Dependent Manner

Deregulated expression of MYC family oncogenes occurs frequently in human cancer and is often associated with aggressive disease and poor prognosis. While MYC is a highly warranted target, it has been considered “undruggable,” and no specific anti-MYC drugs are available in the clinic. We recently i...

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Detalles Bibliográficos
Autores principales: Castell, Alina, Yan, Qinzi, Fawkner, Karin, Bazzar, Wesam, Zhang, Fan, Wickström, Malin, Alzrigat, Mohammad, Franco, Marcela, Krona, Cecilia, Cameron, Donald P., Dyberg, Cecilia, Olsen, Thale Kristin, Verschut, Vasiliki, Schmidt, Linnéa, Lim, Sheryl Y., Mahmoud, Loay, Hydbring, Per, Lehmann, Sören, Baranello, Laura, Nelander, Sven, Johnsen, John Inge, Larsson, Lars-Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980915/
https://www.ncbi.nlm.nih.gov/pubmed/36874405
http://dx.doi.org/10.1158/2767-9764.CRC-21-0019

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