Redirecting T-cell Activity with Anti-BCMA/Anti-CD3 Bispecific Antibodies in Chronic Lymphocytic Leukemia and Other B-cell Lymphomas

T-cell redirecting bispecific antibodies hold high promise for treatment of B-cell malignancies. B-cell maturation antigen (BCMA) exhibits high expression on normal and malignant mature B cells including plasma cells, which can be enhanced by inhibition of γ-secretase. BCMA is considered a validated...

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Detalles Bibliográficos
Autores principales: Martens, Anne W.J., Rietveld, Joanne M., de Boer, Renate, Peters, Fleur S., Ngo, An, van Mil, Lotte W.H.G., de Heer, Koen, Spaargaren, Marcel, Verkleij, Christie P.M., van de Donk, Niels W.C.J., Adams, Homer C., Eldering, Eric, van Noesel, Carel J.M., Verona, Raluca, Kater, Arnon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981202/
https://www.ncbi.nlm.nih.gov/pubmed/36875718
http://dx.doi.org/10.1158/2767-9764.CRC-22-0083

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