Safety and Efficacy of Engineered Toxin Body MT-3724 in Relapsed or Refractory B-cell Non-Hodgkin's Lymphomas and Diffuse Large B-cell Lymphoma

MT-3724, a novel engineered toxin body comprised of an anti-CD20 single-chain variable fragment genetically fused to Shiga-like Toxin A subunit, is capable of binding to and internalizing against CD20, inducing cell killing via permanent ribosomal inactivation. This study evaluated MT-3724 in patien...

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Detalles Bibliográficos
Autores principales: Hamlin, Paul A., Musteata, Vasile, Park, Steven I., Burnett, Christine, Dabovic, Kristina, Strack, Thomas, Williams, Eric T., Anand, Banmeet S., Higgins, Jack P., Persky, Daniel O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981212/
https://www.ncbi.nlm.nih.gov/pubmed/36875713
http://dx.doi.org/10.1158/2767-9764.CRC-22-0056

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