Cargando…

Tumor Purity in Preclinical Mouse Tumor Models

Tumor biology is determined not only by immortal cancer cells but also by the tumor microenvironment consisting of noncancerous cells and extracellular matrix, together they dictate the pathogenesis and response to treatments. Tumor purity is the proportion of cancer cells in a tumor. It is a fundam...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qian, Wubin, Chen, Xiaobo, Sheng, Yanghui, Zhang, Likun, Wang, Jingjing, Song, Zhenzhen, Li, Qi-Xiang, Guo, Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981214/ https://www.ncbi.nlm.nih.gov/pubmed/36875715 http://dx.doi.org/10.1158/2767-9764.CRC-21-0126

Ejemplares similares

Authentication, characterization and contamination detection of cell lines, xenografts and organoids by barcode deep NGS sequencing
por: Chen, Xiaobo, et al.
Publicado: (2020)

Tumor purity as a prognosis and immunotherapy relevant feature in cervical cancer
por: Deng, Yali, et al.
Publicado: (2021)

Maximizing the potential of aggressive mouse tumor models in preclinical drug testing
por: Elghetany, M. Tarek, et al.
Publicado: (2021)

Biased Influences of Low Tumor Purity on Mutation Detection in Cancer
por: Cheng, Jun, et al.
Publicado: (2020)

Tumor purity as a prognosis and immunotherapy relevant feature in gastric cancer
por: Gong, Zhe, et al.
Publicado: (2020)

MethylPurify: tumor purity deconvolution and differential methylation detection from single tumor DNA methylomes
por: Zheng, Xiaoqi, et al.
Publicado: (2014)

Systematic Assessment of Tumor Purity and Its Clinical Implications
por: Haider, Syed, et al.
Publicado: (2020)

Tumor purity–associated genes influence hepatocellular carcinoma prognosis and tumor microenvironment
por: Zhao, Yan, et al.
Publicado: (2023)

Circulating Tumor Cell Analysis in Preclinical Mouse Models of Metastasis
por: Kitz, Jenna, et al.
Publicado: (2018)

An HNSCC syngeneic mouse model for tumor immunology research and preclinical evaluation
por: Fu, You, et al.
Publicado: (2020)

Tumor Purity Coexpressed Genes Related to Immune Microenvironment and Clinical Outcomes of Lung Adenocarcinoma
por: Bai, Ming, et al.
Publicado: (2021)

Comprehensive Characterization of Tumor Purity and Its Clinical Implications in Gastric Cancer
por: Lou, Shenghan, et al.
Publicado: (2022)

Putative biomarkers for predicting tumor sample purity based on gene expression data
por: Li, Yuanyuan, et al.
Publicado: (2019)

Centrifugation affects the purity of liquid biopsy‐based tumor biomarkers
por: Rikkert, Linda G., et al.
Publicado: (2018)

The Analysis of Gene Expression Data Incorporating Tumor Purity Information
por: Ahn, Seungjun, et al.
Publicado: (2021)

Mouse Tumor-Bearing Models as Preclinical Study Platforms for Oral Squamous Cell Carcinoma
por: Li, Qiang, et al.
Publicado: (2020)

Optimization on the dose and time of nicaraven administration for mitigating the side effects of radiotherapy in a preclinical tumor-bearing mouse model
por: Xu, Yong, et al.
Publicado: (2022)

Accurately estimating the length distributions of genomic micro-satellites by tumor purity deconvolution
por: Wang, Yixuan, et al.
Publicado: (2020)

Rapid preliminary purity evaluation of tumor biopsies using deep learning approach
por: Fan, Fei, et al.
Publicado: (2020)

Molecular Imaging of Tumor-Infiltrating Macrophages in a Preclinical Mouse Model of Breast Cancer
por: Sun, Xianlei, et al.
Publicado: (2015)

Advances in the Application of Preclinical Models in Photodynamic Therapy for Tumor: A Narrative Review
por: Yu, Rong, et al.
Publicado: (2023)

Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro Functional Studies, and Cynomolgus Macaque Toxicology
por: Selby, Mark J., et al.
Publicado: (2016)

Assessment of MicroRNAs Associated with Tumor Purity by Random Forest Regression
por: Nam, Dong-Yeon, et al.
Publicado: (2022)

In vivo models of brain tumors: roles of genetically engineered mouse models in understanding tumor biology and use in preclinical studies
por: Simeonova, Iva, et al.
Publicado: (2014)

Purification of differentiated tumor cells from medulloblastoma for transplantation into mouse cerebellum
por: Yang, Yijun, et al.
Publicado: (2021)

An Integrated Analysis of Tumor Purity of Common Central Nervous System Tumors in Children Based on Machine Learning Methods
por: Yang, Jian, et al.
Publicado: (2021)

Correction: Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro Functional Studies, and Cynomolgus Macaque Toxicology
por: Selby, Mark J., et al.
Publicado: (2016)

Nanoplateletsomes restrain metastatic tumor formation through decoy and active targeting in a preclinical mouse model
por: Zhang, Longlong, et al.
Publicado: (2022)

Identification of different types of tumors based on photoacoustic spectral analysis: preclinical feasibility studies on skin tumors
por: Zhang, Mengjiao, et al.
Publicado: (2023)

Leveraging Spatial Variation in Tumor Purity for Improved Somatic Variant Calling of Archival Tumor Only Samples
por: Halperin, Rebecca F., et al.
Publicado: (2019)

Clinical advantage of targeted sequencing for unbiased tumor mutational burden estimation in samples with low tumor purity
por: Hong, Tae Hee, et al.
Publicado: (2020)

Tumor-Promoting ATAD2 and Its Preclinical Challenges
por: Liu, Haicheng, et al.
Publicado: (2022)

Identification of Signature Genes and Characterizations of Tumor Immune Microenvironment and Tumor Purity in Lung Adenocarcinoma Based on Machine Learning
por: Feng, Haiming, et al.
Publicado: (2022)

InfiniumPurify: An R package for estimating and accounting for tumor purity in cancer methylation research
por: Qin, Yufang, et al.
Publicado: (2018)

Estimating and accounting for tumor purity in the analysis of DNA methylation data from cancer studies
por: Zheng, Xiaoqi, et al.
Publicado: (2017)

Integrated RNA and DNA sequencing improves mutation detection in low purity tumors
por: Wilkerson, Matthew D., et al.
Publicado: (2014)

Accurate tumor purity determination is critical for the analysis of homologous recombination deficiency (HRD)
por: Menzel, Michael, et al.
Publicado: (2023)

Real-time monitoring of tumor progression and drug responses in a preclinical mouse model of prostate cancer
por: Xu, Peng, et al.
Publicado: (2016)

A new method for constructing tumor specific gene co-expression networks based on samples with tumor purity heterogeneity
por: Petralia, Francesca, et al.
Publicado: (2018)

VCF2CNA: A tool for efficiently detecting copy-number alterations in VCF genotype data and tumor purity
por: Putnam, Daniel K., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_dn5t4hp5aetti53qsopaufp0m7