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Report of the first seven agents in the I-SPY COVID trial: a phase 2, open label, adaptive platform randomised controlled trial
BACKGROUND: An urgent need exists to rapidly screen potential therapeutics for severe COVID-19 or other emerging pathogens associated with high morbidity and mortality. METHODS: Using an adaptive platform design created to rapidly evaluate investigational agents, hospitalised patients with severe CO...
Formato: | Online Artículo Texto |
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Lenguaje: | English |
Publicado: |
Elsevier
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981330/ https://www.ncbi.nlm.nih.gov/pubmed/36883141 http://dx.doi.org/10.1016/j.eclinm.2023.101889 |