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The two faces of pyocyanin - why and how to steer its production?

The ambiguous nature of pyocyanin was noted quite early after its discovery. This substance is a recognized Pseudomonas aeruginosa virulence factor that causes problems in cystic fibrosis, wound healing, and microbiologically induced corrosion. However, it can also be a potent chemical with potentia...

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Autores principales: Jabłońska, Joanna, Augustyniak, Adrian, Dubrowska, Kamila, Rakoczy, Rafał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981528/
https://www.ncbi.nlm.nih.gov/pubmed/36864230
http://dx.doi.org/10.1007/s11274-023-03548-w
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author Jabłońska, Joanna
Augustyniak, Adrian
Dubrowska, Kamila
Rakoczy, Rafał
author_facet Jabłońska, Joanna
Augustyniak, Adrian
Dubrowska, Kamila
Rakoczy, Rafał
author_sort Jabłońska, Joanna
collection PubMed
description The ambiguous nature of pyocyanin was noted quite early after its discovery. This substance is a recognized Pseudomonas aeruginosa virulence factor that causes problems in cystic fibrosis, wound healing, and microbiologically induced corrosion. However, it can also be a potent chemical with potential use in a wide variety of technologies and applications, e.g. green energy production in microbial fuel cells, biocontrol in agriculture, therapy in medicine, or environmental protection. In this mini-review, we shortly describe the properties of pyocyanin, its role in the physiology of Pseudomonas and show the ever-growing interest in it. We also summarize the possible ways of modulating pyocyanin production. We underline different approaches of the researchers that aim either at lowering or increasing pyocyanin production by using different culturing methods, chemical additives, physical factors (e.g. electromagnetic field), or genetic engineering techniques. The review aims to present the ambiguous character of pyocyanin, underline its potential, and signalize the possible further research directions.
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spelling pubmed-99815282023-03-04 The two faces of pyocyanin - why and how to steer its production? Jabłońska, Joanna Augustyniak, Adrian Dubrowska, Kamila Rakoczy, Rafał World J Microbiol Biotechnol Review The ambiguous nature of pyocyanin was noted quite early after its discovery. This substance is a recognized Pseudomonas aeruginosa virulence factor that causes problems in cystic fibrosis, wound healing, and microbiologically induced corrosion. However, it can also be a potent chemical with potential use in a wide variety of technologies and applications, e.g. green energy production in microbial fuel cells, biocontrol in agriculture, therapy in medicine, or environmental protection. In this mini-review, we shortly describe the properties of pyocyanin, its role in the physiology of Pseudomonas and show the ever-growing interest in it. We also summarize the possible ways of modulating pyocyanin production. We underline different approaches of the researchers that aim either at lowering or increasing pyocyanin production by using different culturing methods, chemical additives, physical factors (e.g. electromagnetic field), or genetic engineering techniques. The review aims to present the ambiguous character of pyocyanin, underline its potential, and signalize the possible further research directions. Springer Netherlands 2023-02-18 2023 /pmc/articles/PMC9981528/ /pubmed/36864230 http://dx.doi.org/10.1007/s11274-023-03548-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review
Jabłońska, Joanna
Augustyniak, Adrian
Dubrowska, Kamila
Rakoczy, Rafał
The two faces of pyocyanin - why and how to steer its production?
title The two faces of pyocyanin - why and how to steer its production?
title_full The two faces of pyocyanin - why and how to steer its production?
title_fullStr The two faces of pyocyanin - why and how to steer its production?
title_full_unstemmed The two faces of pyocyanin - why and how to steer its production?
title_short The two faces of pyocyanin - why and how to steer its production?
title_sort two faces of pyocyanin - why and how to steer its production?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981528/
https://www.ncbi.nlm.nih.gov/pubmed/36864230
http://dx.doi.org/10.1007/s11274-023-03548-w
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