Ploidy-stratified single cardiomyocyte transcriptomics map Zinc Finger E-Box Binding Homeobox 1 to underly cardiomyocyte proliferation before birth

Whereas cardiomyocytes (CMs) in the fetal heart divide, postnatal CMs fail to undergo karyokinesis and/or cytokinesis and therefore become polyploid or binucleated, a key process in terminal CM differentiation. This switch from a diploid proliferative CM to a terminally differentiated polyploid CM r...

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Detalles Bibliográficos
Autores principales: Bak, Sara Thornby, Harvald, Eva Bang, Ellman, Ditte Gry, Mathiesen, Sabrina Bech, Chen, Ting, Fang, Shu, Andersen, Kristian Skriver, Fenger, Christina Dühring, Burton, Mark, Thomassen, Mads, Andersen, Ditte Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981540/
https://www.ncbi.nlm.nih.gov/pubmed/36862248
http://dx.doi.org/10.1007/s00395-023-00979-2

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