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ERdj5 protects goblet cells from endoplasmic reticulum stress-mediated apoptosis under inflammatory conditions

Endoplasmic reticulum stress is closely associated with the onset and progression of inflammatory bowel disease. ERdj5 is an endoplasmic reticulum-resident protein disulfide reductase that mediates the cleavage and degradation of misfolded proteins. Although ERdj5 expression is significantly higher...

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Detalles Bibliográficos
Autores principales: Jeong, Hyunjin, Hong, Eun-Hye, Ahn, Jae-Hee, Cho, Jaewon, Jeong, Jae-Hyeon, Kim, Chae-Won, Yoon, Byung-Il, Koo, Ja Hyun, Park, Yun-Yong, Yang, Yoon Mee, Iwawaki, Takao, Vallance, Bruce A., Chang, Sun-Young, Ko, Hyun-Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981579/
https://www.ncbi.nlm.nih.gov/pubmed/36759578
http://dx.doi.org/10.1038/s12276-023-00945-x