Cargando…

Case report: A case of rectal metastatic squamous cell carcinoma from the esophagus

Esophageal cancer is prone to distant metastasis, and the prognosis is very poor; the occurrence of intestinal metastasis is extremely rare, with atypical clinical manifestations. We report a case of rectal metastasis after surgery for esophageal squamous cell carcinoma. The patient was a 63-year-ol...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Junni, Zhang, Shuai, Chen, Jiawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981638/
https://www.ncbi.nlm.nih.gov/pubmed/36874084
http://dx.doi.org/10.3389/fonc.2023.1092868
_version_ 1784900150157639680
author Chen, Junni
Zhang, Shuai
Chen, Jiawei
author_facet Chen, Junni
Zhang, Shuai
Chen, Jiawei
author_sort Chen, Junni
collection PubMed
description Esophageal cancer is prone to distant metastasis, and the prognosis is very poor; the occurrence of intestinal metastasis is extremely rare, with atypical clinical manifestations. We report a case of rectal metastasis after surgery for esophageal squamous cell carcinoma. The patient was a 63-year-old male who was admitted to the hospital due to progressive dysphagia. He was diagnosed with moderately differentiated esophageal squamous cell carcinoma after the surgery. He was not treated with chemoradiotherapy after surgery and had recurrent blood in his stool at 9 months post-surgery; rectal metastasis of esophageal squamous carcinoma was diagnosed based on postoperative pathology. Because the patient had a positive rectal margin, we used adjuvant chemoradiotherapy and carrelizumab immunotherapy, achieving very good short-term efficacy. The patient is currently in a state of tumor-free survival and is still being closely followed up and treated. Through this case report, we hope to deepen understanding of rare metastasis of esophageal squamous cell carcinoma and actively promote local radiotherapy plus chemotherapy and immunotherapy to improve survival.
format Online
Article
Text
id pubmed-9981638
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-99816382023-03-04 Case report: A case of rectal metastatic squamous cell carcinoma from the esophagus Chen, Junni Zhang, Shuai Chen, Jiawei Front Oncol Oncology Esophageal cancer is prone to distant metastasis, and the prognosis is very poor; the occurrence of intestinal metastasis is extremely rare, with atypical clinical manifestations. We report a case of rectal metastasis after surgery for esophageal squamous cell carcinoma. The patient was a 63-year-old male who was admitted to the hospital due to progressive dysphagia. He was diagnosed with moderately differentiated esophageal squamous cell carcinoma after the surgery. He was not treated with chemoradiotherapy after surgery and had recurrent blood in his stool at 9 months post-surgery; rectal metastasis of esophageal squamous carcinoma was diagnosed based on postoperative pathology. Because the patient had a positive rectal margin, we used adjuvant chemoradiotherapy and carrelizumab immunotherapy, achieving very good short-term efficacy. The patient is currently in a state of tumor-free survival and is still being closely followed up and treated. Through this case report, we hope to deepen understanding of rare metastasis of esophageal squamous cell carcinoma and actively promote local radiotherapy plus chemotherapy and immunotherapy to improve survival. Frontiers Media S.A. 2023-02-17 /pmc/articles/PMC9981638/ /pubmed/36874084 http://dx.doi.org/10.3389/fonc.2023.1092868 Text en Copyright © 2023 Chen, Zhang and Chen https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Chen, Junni
Zhang, Shuai
Chen, Jiawei
Case report: A case of rectal metastatic squamous cell carcinoma from the esophagus
title Case report: A case of rectal metastatic squamous cell carcinoma from the esophagus
title_full Case report: A case of rectal metastatic squamous cell carcinoma from the esophagus
title_fullStr Case report: A case of rectal metastatic squamous cell carcinoma from the esophagus
title_full_unstemmed Case report: A case of rectal metastatic squamous cell carcinoma from the esophagus
title_short Case report: A case of rectal metastatic squamous cell carcinoma from the esophagus
title_sort case report: a case of rectal metastatic squamous cell carcinoma from the esophagus
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981638/
https://www.ncbi.nlm.nih.gov/pubmed/36874084
http://dx.doi.org/10.3389/fonc.2023.1092868
work_keys_str_mv AT chenjunni casereportacaseofrectalmetastaticsquamouscellcarcinomafromtheesophagus
AT zhangshuai casereportacaseofrectalmetastaticsquamouscellcarcinomafromtheesophagus
AT chenjiawei casereportacaseofrectalmetastaticsquamouscellcarcinomafromtheesophagus