Microsatellite instability-related prognostic risk score (MSI-pRS) defines a subset of lung squamous cell carcinoma (LUSC) patients with genomic instability and poor clinical outcome

Background: Lung squamous cell carcinoma (LUSC) shares less typical onco-drivers and target resistance, but a high overall mutation rate and marked genomic complexity. Mismatch repair (MMR) deficiency leads to microsatellite instability (MSI) and genomic instability. MSI is not an ideal option for p...

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Detalles Bibliográficos
Autores principales: Hu, Zixin, Liu, Zhening, Zheng, Jiabin, Peng, Yanmei, Lu, Xingyu, Li, Jia, Tan, Kexin, Cui, Huijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981642/
https://www.ncbi.nlm.nih.gov/pubmed/36873930
http://dx.doi.org/10.3389/fgene.2023.1061002

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