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rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly

Biogenesis of the large ribosomal (60S) subunit involves the assembly of three rRNAs and 46 proteins, a process requiring approximately 70 ribosome biogenesis factors (RBFs) that bind and release the pre-60S at specific steps along the assembly pathway. The methyltransferase Spb1 and the K-loop GTPa...

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Detalles Bibliográficos
Autores principales: Sekulski, Kamil, Cruz, Victor Emmanuel, Weirich, Christine S., Erzberger, Jan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981671/
https://www.ncbi.nlm.nih.gov/pubmed/36864048
http://dx.doi.org/10.1038/s41467-023-36867-5