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Retinol dehydrogenase 10 reduction mediated retinol metabolism disorder promotes diabetic cardiomyopathy in male mice

Diabetic cardiomyopathy is a primary myocardial injury induced by diabetes with complex pathogenesis. In this study, we identify disordered cardiac retinol metabolism in type 2 diabetic male mice and patients characterized by retinol overload, all-trans retinoic acid deficiency. By supplementing typ...

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Detalles Bibliográficos
Autores principales: Wu, Yandi, Huang, Tongsheng, Li, Xinghui, Shen, Conghui, Ren, Honglin, Wang, Haiping, Wu, Teng, Fu, Xinlu, Deng, Shijie, Feng, Ziqi, Xiong, Shijie, Li, Hui, Gao, Saifei, Yang, Zhenyu, Gao, Fei, Dong, Lele, Cheng, Jianding, Cai, Weibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9981688/
https://www.ncbi.nlm.nih.gov/pubmed/36864033
http://dx.doi.org/10.1038/s41467-023-36837-x